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ENZYMES WITHOUT COMPROMISE

We offer CLīM™- powered recombinant protein solutions

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Trusted by industry leaders

Enzyme

Needed

Available

Commercially?

Yes

In- House

Expertise?

Quality & Cost

Acceptable?

Yes

Make

in-house

Outsource

Compare offerings from commercial suppliers

Spend weeks or months developing products

Trial and error to find reagent that works

Costs savings possible, but opportunity costs of resources committed to non-critical path development

Costs can be prohibitive, even for large companies

About TriAltus Bioscience

Taking the pain
out of outsourcing

At TriAltus, we understand the real-world challenges research teams face when it comes to sourcing high-quality recombinant proteins. Specialty enzymes are essential tools in drug discovery, diagnostics, and synthetic biology — but too often, their cost forces teams to bring production in-house, diverting time, talent, and equipment away from core scientific work.

We believe you shouldn’t have to choose
between quality and affordability.

That’s why we built our enzyme platform around CLīM™, a proprietary purification technology that delivers ultra-pure, high-performance proteins in a single purification step. By dramatically lowering the cost of manufacturing, we’re able to pass meaningful savings on to you — making it easier than ever to source the reagents you need without sacrificing quality or scalability.

Whether you're advancing a CRISPR workflow, building a diagnostic assay, or scaling a bioproduction process, TriAltus gives you access to the performance you expect — at a price that lets your team stay focused on what matters most.

Purity, performance, price — you don’t have to compromise.

By the numbers

50%+

Average purity

50%+

Average purity

50%+

Average purity

higher avg titer

15%

lower avg cost

15%

lower avg cost

15%

lower avg cost

Years of service

Customers

Technology

Powered by CLīM™

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

CLIM Technology

By leveraging our CLīM™ technology and expertise, you save time, labor, and equipment costs and gain a dependable source of your protein delivered when and how you need it.

CLIM Technology

By leveraging our CLīM™ technology and expertise, you save time, labor, and equipment costs and gain a dependable source of your protein delivered when and how you need it.

CLIM Technology

By leveraging our CLīM™ technology and expertise, you save time, labor, and equipment costs and gain a dependable source of your protein delivered when and how you need it.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Dr. Jennifer Doudna was a co-inventor of CRISPR-Cas 9 gene editing technology, for which she earned the Nobel Prize in Chemistry in 2020. Since 2021, scientists in Doudna’s lab at UC Berkeley have produced more than 100 CRISPR enzymes using TriAltus’ CLīM™ purification system. The same purification technology trusted in CRISPR discovery is behind every TriAltus enzyme.

Recent citations:

Learn more -> about the study in Nature Biotechnology (2024)

Learn more -> about the study in Nucleic Acids Research (2025)

Dr. Jennifer Doudna in Berkeley, Calif., on Jan. 18, 2019.Anastasiia Sapon—The New York Times/Redux

What we do for you

Your Protein, Delivered

Genomic Enzymes

High-purity enzymes optimized for molecular biology workflows, including PCR, isothermal amplification, and CRISPR applications.

Genomic Enzymes

High-purity enzymes optimized for molecular biology workflows, including PCR, isothermal amplification, and CRISPR applications.

Genomic Enzymes

High-purity enzymes optimized for molecular biology workflows, including PCR, isothermal amplification, and CRISPR applications.

Other Specialty Enzymes

High-purity recombinant enzymes designed to support a wide range of R&D applications beyond genomics, with a focus on performance, consistency, and scalability.

Other Specialty Enzymes

High-purity recombinant enzymes designed to support a wide range of R&D applications beyond genomics, with a focus on performance, consistency, and scalability.

Other Specialty Enzymes

High-purity recombinant enzymes designed to support a wide range of R&D applications beyond genomics, with a focus on performance, consistency, and scalability.

Pilot Services

Development of custom proteins using our proprietary CLīM™ system — the ideal starting point for early-stage discovery with a clear path to scalable, cost-effective production.

Pilot Services

Development of custom proteins using our proprietary CLīM™ system — the ideal starting point for early-stage discovery with a clear path to scalable, cost-effective production.

Pilot Services

Development of custom proteins using our proprietary CLīM™ system — the ideal starting point for early-stage discovery with a clear path to scalable, cost-effective production.

Contract Manufacturing

ISO 13485–compliant production of research- or diagnostic-grade enzymes, with batch-to-batch consistency and flexible supply options.

Contract Manufacturing

ISO 13485–compliant production of research- or diagnostic-grade enzymes, with batch-to-batch consistency and flexible supply options.

Contract Manufacturing

ISO 13485–compliant production of research- or diagnostic-grade enzymes, with batch-to-batch consistency and flexible supply options.

Capabilities and Add on Services

TriAltus Capabilities

Solubility testing

Early solubility checks to ensure protein stability and usability.

Solubility testing

Early solubility checks to ensure protein stability and usability.

Solubility testing

Early solubility checks to ensure protein stability and usability.

FPLC purification

High-resolution purification for precise, reproducible results.

FPLC purification

High-resolution purification for precise, reproducible results.

FPLC purification

High-resolution purification for precise, reproducible results.

Standard QC quantitation

Reliable quality control with accurate protein quantification.

Standard QC quantitation

Reliable quality control with accurate protein quantification.

Standard QC quantitation

Reliable quality control with accurate protein quantification.

ISO13485-compliant manufacturing

Strict regulatory compliance for diagnostic-grade proteins.

ISO13485-compliant manufacturing

Strict regulatory compliance for diagnostic-grade proteins.

ISO13485-compliant manufacturing

Strict regulatory compliance for diagnostic-grade proteins.